Negative Pressure Pulmonary Edema (NPPE)

  • Christine Nagel Texas Christian University


Negative pressure pulmonary edema (NPPE) is a rare but dangerous complication of general anesthesia that can lead to detrimental results, including anoxic brain injury or death, if not promptly recognized and treated. The purpose of this research is to educate professionals on the etiology, signs, symptoms, treatments, risk factors, and preventions to aid in the early recognition and treatment of NPPE. With a mortality rate up to 5%, proper provider education on NPPE is necessary to prevent its occurrence. This project followed a case report of an 18-year-old male who developed NPPE after a pilonidal cyst removal under general anesthesia.

How to Cite
NAGEL, Christine. Negative Pressure Pulmonary Edema (NPPE). Anesthesia eJournal, [S.l.], v. 10, n. 3, p. 1-2, feb. 2023. ISSN 2333-2611. Available at: <>. Date accessed: 23 apr. 2024.